

History: Young man with 3 days of chest tightness, dysnpea, fever, and nausea.
what is the possible diagnosis:
A Germ cell tumor.
B Lymphoma.
C Sarcoma.
D Thymic tumor.
E All of the above belong to the differential diagnosis
Can you select the correct answer
B T or F Mass is mostly necrotic.
C T or F There is evidence of pericardial involvement.
Can you select the actual diagnosis?
A Germ cell tumor.
B Lymphoma.
C Sarcoma.
D Thymic tumor.
E None of the above.
Key points:
Diffuse large B-cell lymphoma (DLBCL) is a fast-growing, aggressive form of non-Hodgkin's lymphoma (NHL)
There are more than 20 types of NHL, DLBCL is the most common type, making up about 30 percent of all lymphomas
Diffuse large B-cell lymphoma can be fatal if left untreated, but with timely and appropriate treatment, up to half of all patients are curable.
This subtype of DLBCL within the chest cavity that usually involvse the thymus.
Primary mediastinal large B-cell lymphoma comprises 7 percent of all diffuse large B-cell lymphomas and accounts for 2.4 percent of all non-Hodgkin's lymphomas. If this subtype of diffuse large B-cell lymphoma recurs, it can cause problems with other organs, including the liver, gastrointestinal tract, kidneys, ovaries, and central nervous system.
The five-year survival rate of patients with DLBCL is between 26 and 73 percent.
answer: E, C, B
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