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Wednesday, 8 April 2009

train in single best answer even with image



History: Young man with 3 days of chest tightness, dysnpea, fever, and nausea.



what is the possible diagnosis:

A Germ cell tumor.

B Lymphoma.

C Sarcoma.

D Thymic tumor.

E All of the above belong to the differential diagnosis


Can you select the correct answer

A- T or F SVC is occluded.

B T or F Mass is mostly necrotic.

C T or F There is evidence of pericardial involvement.



Can you select the actual diagnosis?

A Germ cell tumor.

B Lymphoma.

C Sarcoma.

D Thymic tumor.

E None of the above.


Key points:

  • Diffuse large B-cell lymphoma (DLBCL) is a fast-growing, aggressive form of non-Hodgkin's lymphoma (NHL)

  • There are more than 20 types of NHL, DLBCL is the most common type, making up about 30 percent of all lymphomas

  • Diffuse large B-cell lymphoma can be fatal if left untreated, but with timely and appropriate treatment, up to half of all patients are curable.

  • This subtype of DLBCL within the chest cavity that usually involvse the thymus.

  • Primary mediastinal large B-cell lymphoma comprises 7 percent of all diffuse large B-cell lymphomas and accounts for 2.4 percent of all non-Hodgkin's lymphomas. If this subtype of diffuse large B-cell lymphoma recurs, it can cause problems with other organs, including the liver, gastrointestinal tract, kidneys, ovaries, and central nervous system.

  • The five-year survival rate of patients with DLBCL is between 26 and 73 percent.

answer: E, C, B

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